Central Macedonia Vacations & Trips from $876

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Your Central Macedonia Vacation

When adventure calls, answer it with a tailor-made vacation package to Central Macedonia. Wherever your travels lead and whatever your plans are, get set to discover a destination with so much to offer. With so many things to see on a trip to Central Macedonia, it can be hard to know where to start. Kick off your travels in Thessaloniki at White Tower of Thessaloniki and Tsimiski Street — two popular attractions here. Another top city to add to your itinerary is Kassandra. Don't miss Kalithea Beach and Siviri Beach. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next dream Central Macedonia vacation.

Top destinations in Central Macedonia

Thessaloniki which includes a city and general coastal views
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Thessaloniki

Thessaloniki

The Latest Central Macedonia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Met Hotel, a member of Design Hotels

The Met Hotel, a member of Design Hotels

5 out of 5
per person
Oct 20 - Oct 25
found 24 hours ago
Roundtrip non-stop flight included
New York (JFK) to Thessaloniki (SKG)
9.2/10 Wonderful! (821 reviews)
Amazing experience will be back in the future

Reviewed on Jul 12, 2025

Domes Noruz Kassandra - Adults Only, Halkidiki

Domes Noruz Kassandra - Adults Only, Halkidiki

5 out of 5
Save 100% on your flight
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip flight included
New York (JFK) to Thessaloniki (SKG)
9.4/10 Exceptional! (111 reviews)
Everything about this property from the moment you get to the gate is excellent. Checkin was smooth, property is beautiful! Extended my stay twice

Reviewed on Jul 1, 2025

Ajul Luxury Hotel & Spa Resort, a Registry Collection Hotel

Ajul Luxury Hotel & Spa Resort, a Registry Collection Hotel

5 out of 5
Save 100% on your flight
per person
Sep 13 - Sep 20
found 1 day ago
Roundtrip flight included
New York (NYC) to Thessaloniki (SKG)
8/10 Very Good! (8 reviews)
Avaton Luxury Beach Resort - Relais & Chateaux

Avaton Luxury Beach Resort - Relais & Chateaux

5 out of 5
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip flight included
New York (JFK) to Thessaloniki (SKG)
8.6/10 Excellent! (24 reviews)
Truely 5 stars services

Reviewed on Jul 15, 2025

PALMA VILLAGE HOTEL by Greek Pride

PALMA VILLAGE HOTEL by Greek Pride

4 out of 5
per person
Sep 13 - Sep 20
found 1 day ago
Roundtrip flight included
New York (NYC) to Thessaloniki (SKG)
No reviews

Where to stay in Central Macedonia

Get a lay of the land and find the perfect place to stay Learn more about Central Macedonia
Church of Hagia Sophia showing a church or cathedral

Thessaloniki City Centre

1 out of top 10 points of interest in this area
4.5/5(202 area reviews)

If you're spending time in Thessaloniki City Centre, check out sights like Tsimiski Street or Church of Hagia Sophia and hop on the metro to see more the city at Agias Sofias Metro Station or Venizelou Metro Station.

Find hotels in Thessaloniki City Centre

Central Macedonia Hotel Deals

City Hotel Thessaloniki

City Hotel Thessaloniki

4 out of 5
11 Komninon Street, Thessaloniki, Central Macedonia
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $131 total per night from Aug 17 to Aug 18
$131 total
Aug 17 - Aug 18
Total includes taxes and fees
8.4/10 Very Good! (604 reviews)
"As always our stay at City Hotel was incredible, they are so welcoming"

Reviewed on Aug 9, 2025

City Hotel Thessaloniki
Cora Hotel & Spa

Cora Hotel & Spa

5 out of 5
Kassandra, Chalkidiki, Kassandra, Central Macedonia
$225 nightly
The price is $273 total per night from Sep 12 to Sep 13
$273 total
Sep 12 - Sep 13
Total includes taxes and fees
8.4/10 Very Good! (52 reviews)
Excellent choice
"Friendly staff, very helpful. Excellent food, and incredible pools."

Reviewed on Jul 29, 2025

Cora Hotel & Spa
Daios Luxury Living

Daios Luxury Living

5 out of 5
Nikis Avenue 59, Thessaloniki, Central Macedonia
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $190 total per night from Aug 14 to Aug 15
$190 total
Aug 14 - Aug 15
Total includes taxes and fees
9.6/10 Exceptional! (714 reviews)
"It feels like you're on a cruise boat!"

Reviewed on Aug 2, 2025

Daios Luxury Living
See all 4,078 properties in Central Macedonia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Central Macedonia

Greece

Kalithea Beach

4.5/5(3 reviews)

Why not spend a carefree afternoon at Kalithea Beach during your travels in Kallithea? Stroll along the area's seaside or simply enjoy its restaurants.

Kalithea Beach
Aristotelous Square featuring a square or plaza, general coastal views and a coastal town

Aristotelous Square

4.5/5(134 reviews)

Visit Thessaloniki’s main square, a busy gathering place for locals and the site of major events throughout the year.

Aristotelous Square
White Tower of Thessaloniki featuring heritage elements

White Tower of Thessaloniki

4.5/5(129 reviews)

This distinctly shaped tower has evolved alongside Thessaloniki over the centuries and now houses a museum dedicated to the city’s history.

White Tower of Thessaloniki

What to do in Central Macedonia

Single day rail trip from Thessaloniki to Meteora

Single day rail trip from Thessaloniki to Meteora

$112
per adult
Single day rail trip from Thessaloniki to Meteora
Halkidiki Blue Lagoon Cruise from Thessaloniki with Lunch

Halkidiki Blue Lagoon Cruise from Thessaloniki with Lunch

$85
per adult
Halkidiki Blue Lagoon Cruise from Thessaloniki with Lunch
Picture 1 for Activity Thessaloniki: Halkidiki Beach-Hopping with Swimming

Thessaloniki: Halkidiki Beach-Hopping with Swimming

$93
per adult
Thessaloniki: Halkidiki Beach-Hopping with Swimming
See all activities in Central Macedonia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.