Central Macedonia Vacations & Trips from $765

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Your Central Macedonia Vacation

When adventure calls, answer it with a tailor-made vacation package to Central Macedonia. Wherever your travels lead and whatever your plans are, get set to discover a destination with so much to offer. With so many things to see on a trip to Central Macedonia, it can be hard to know where to start. Kick off your travels in Thessaloniki at White Tower of Thessaloniki and Tsimiski Street — two popular attractions here. Another top city to add to your itinerary is Kassandra. Don't miss Kalithea Beach and Siviri Beach. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next dream Central Macedonia vacation.

Top destinations in Central Macedonia

Thessaloniki which includes a city and general coastal views
FlightsFlightsHotelsHotels

Thessaloniki

Thessaloniki

The Latest Central Macedonia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Philippion Hotel

Philippion Hotel

3 out of 5
Price was $860, price is now $765 per person
$765
per person
Nov 7 - Nov 12
found 1 hour ago
Roundtrip non-stop flight included
New York (NYC) to Thessaloniki (SKG)
7.2/10 Good! (91 reviews)
The fresh and healthy area The oxygen of the forest

Reviewed on Dec 16, 2024

The Excelsior Small Luxury Hotels of the World

The Excelsior Small Luxury Hotels of the World

5 out of 5
Thessaloniki City Centre
Price was $1,326, price is now $1,004 per person
$1,004
per person
Nov 6 - Nov 12
found 22 hours ago
Roundtrip non-stop flight included
New York (NYC) to Thessaloniki (SKG)
9.6/10 Exceptional! (392 reviews)
Excelsior was a beautifully renovated property with a lovely welcome and excellent service.

Reviewed on Aug 20, 2025

Noa Hotel

Noa Hotel

4 out of 5
Thessaloniki City Centre
Price was $1,262, price is now $996 per person
$996
per person
Nov 6 - Nov 12
found 22 hours ago
Roundtrip non-stop flight included
New York (NYC) to Thessaloniki (SKG)
9.4/10 Exceptional! (76 reviews)
Better than expected

Reviewed on Sep 13, 2025

Bahar Boutique Hotel

Bahar Boutique Hotel

4 out of 5
Thessaloniki City Centre
Price was $1,112, price is now $948 per person
$948
per person
Nov 7 - Nov 12
found 1 hour ago
Roundtrip non-stop flight included
New York (NYC) to Thessaloniki (SKG)
9.4/10 Exceptional! (82 reviews)
It was so good … Will be back 👍

Reviewed on Jan 13, 2025

Superior One Boutique Hotel

Superior One Boutique Hotel

4 out of 5
Thessaloniki City Centre
Price was $1,022, price is now $885 per person
$885
per person
Nov 7 - Nov 12
found 1 hour ago
Roundtrip non-stop flight included
New York (NYC) to Thessaloniki (SKG)
9/10 Wonderful! (78 reviews)
Staff was great and breakfast was excellent

Reviewed on Jul 3, 2025

Where to stay in Central Macedonia

Get a lay of the land and find the perfect place to stay Learn more about Central Macedonia
Church of Hagia Sophia showing a church or cathedral

Thessaloniki City Centre

1 out of top 10 points of interest in this area
4.5/5(202 area reviews)

If you're spending time in Thessaloniki City Centre, check out sights like Tsimiski Street or Rotonda of St. George and hop on the metro to see more the city at Agias Sofias Metro Station or Venizelou Metro Station.

Find hotels in Thessaloniki City Centre

Central Macedonia Hotel Deals

Colors Urban Hotel Thessaloniki

Colors Urban Hotel Thessaloniki

4 out of 5
13 Tsimiski Street, Thessaloniki, Central Macedonia
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $91 total per night from Oct 29 to Oct 30
$91 total
Oct 29 - Oct 30
Total with taxes and fees
9/10 Wonderful! (613 reviews)
"Great location, great staff."

Reviewed on Sep 21, 2025

Colors Urban Hotel Thessaloniki
Capsis Hotel Thessaloniki

Capsis Hotel Thessaloniki

4 out of 5
18 Monastiriou Street, Thessaloniki, Central Macedonia
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $90 total per night from Oct 12 to Oct 13
$90 total
Oct 12 - Oct 13
Total with taxes and fees
8/10 Very Good! (348 reviews)
"Top"

Reviewed on Sep 18, 2025

Capsis Hotel Thessaloniki
City Hotel Thessaloniki

City Hotel Thessaloniki

4 out of 5
11 Komninon Street, Thessaloniki, Central Macedonia
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $141 total per night from Oct 1 to Oct 2
$141 total
Oct 1 - Oct 2
Total with taxes and fees
8.6/10 Excellent! (613 reviews)
"Consistent hospitality. Great location with easy walking to shops, cafes, restaurants and waterfront"

Reviewed on Sep 12, 2025

City Hotel Thessaloniki
See all 4,033 properties in Central Macedonia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Central Macedonia

Greece

Kalithea Beach

Why not spend a carefree afternoon at Kalithea Beach during your travels in Kallithea? Stroll along the area's seaside or simply enjoy its restaurants.

Kalithea Beach
Aristotelous Square featuring a square or plaza, general coastal views and a coastal town

Aristotelous Square

Visit Thessaloniki’s main square, a busy gathering place for locals and the site of major events throughout the year.

Aristotelous Square
White Tower of Thessaloniki featuring heritage elements

White Tower of Thessaloniki

This distinctly shaped tower has evolved alongside Thessaloniki over the centuries and now houses a museum dedicated to the city’s history.

White Tower of Thessaloniki

What to do in Central Macedonia

Thessaloniki Hop-on Hop-off Sightseeing Bus Tour

Thessaloniki Hop-on Hop-off Sightseeing Bus Tour

$19
per adult
Thessaloniki Hop-on Hop-off Sightseeing Bus Tour
Meteora Full Day Tour from Thessaloniki

Meteora Full Day Tour from Thessaloniki

$83
per adult
100% of travellers recommend
Meteora Full Day Tour from Thessaloniki
Picture 1 for Activity Thessaloniki: Halkidiki Beach-Hopping with Swimming

Thessaloniki: Halkidiki Beach-Hopping & Swimming

$93
per adult
Thessaloniki: Halkidiki Beach-Hopping & Swimming
See all activities in Central Macedonia
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.